2-Pyridinecarbonyl chloride, 4-chloro-

2-Pyridinecarbonyl chloride, 4-chloro- - Names and Identifiers

Name	4-Chloro-pyridine-2-carbonyl chloride
Synonyms	4-chloropicolinoyl chloride 4-CHLOROPHCOLINOYL CHLORIDE 4-Chlorpyridin-2-carbonylchlorid 4-chloro-picolinic acid chloride 4-Chloropyridine-2-carbonyl chlorid 4-Chloro-2-pyridinecarbonyl chloride 4-Chloropyridine-2-carbonyl chloride 4-Chloro-pyridine-2-carbonyl chloride 2-Pyridinecarbonyl chloride, 4-chloro- 2-pyridinecarbonyl chloride, 4-chloro- Chlorure de 4-chloropyridine-2-carbonyle (4-chloropyridin-2-yl)(forMyl)chloranuide 4-Chloro-2-(chlorocarbonyl)pyridine, 4-Chloropicolinoyl chloride 4-Chloro-2-(chlorocarbonyl)pyridine, 4-Chloro-2-picolinoyl chloride
CAS	53750-66-6
InChI	InChI=1/C6H3Cl2NO/c7-4-1-2-9-5(3-4)6(8)10/h1-3H

2-Pyridinecarbonyl chloride, 4-chloro- - Physico-chemical Properties

Molecular Formula	C6H3Cl2NO
Molar Mass	176
Density	1.454±0.06 g/cm3(Predicted)
Boling Point	227.2±20.0 °C(Predicted)
Flash Point	91.218°C
Vapor Presure	0.078mmHg at 25°C
pKa	-1.45±0.10(Predicted)
Storage Condition	Room Temprature
Refractive Index	1.566

2-Pyridinecarbonyl chloride, 4-chloro- - Risk and Safety

Hazard Note

Corrosive

2-Pyridinecarbonyl chloride, 4-chloro- - Introduction

chloride is an organic compound whose chemical formula is C6H3Cl2NO and is a colorless to pale yellow liquid in appearance.

Nature:
The chloride has a strong pungent odor and high volatility. It is a relatively stable compound, but it reacts with water and decomposes under humid conditions. It is soluble in some organic solvents, such as ether and chloroform.

Use:
The chloride is often used as an acylating reagent in organic synthesis, and it can be activated as an acyl group for the synthesis of various acyl-containing compounds. It can also be used to prepare other organochlorine compounds and is widely used in industries such as pharmaceuticals, pesticides, dyes and cosmetics.

Preparation Method:
The preparation of chloride is usually obtained by reacting 4-chloropyridine with thionyl chloride. First, 4-chloropyridine was dissolved in dichloromethane, thionyl chloride was added, and the reaction was heated. After completion of the reaction, the target product was obtained by distillation and purification steps.

Safety Information:
chloride is an organochlorine compound, which is irritating and corrosive. Wear appropriate protective equipment to avoid contact with skin and eyes. During use and storage, avoid contact with strong oxidants and strong bases to avoid dangerous reactions. At the same time, it should be operated in a well-ventilated place to avoid inhaling vapors in closed spaces. In case of accidental contact or inhalation, emergency measures should be taken immediately and medical help should be sought.

Last Update：2024-04-09 21:11:58